Searchable abstracts of presentations at key conferences in endocrinology

ea0094p214 | Metabolism, Obesity and Diabetes | SFEBES2023

The effects of physiological and pathophysiological concentrations of fatty acids on lipid droplet accumulation and metabolic function of LHCN-M2 human skeletal muscle cells

Turner Mark , Brett Ryan , Andreou Persefoni , Hodson Leanne , Renshaw Derek

Introduction: Skeletal muscle (SkM) is a major site of carbohydrate and fatty acid (FA) utilisation, where efficient selection between these two substrates is paramount in maintaining metabolic homeostasis. The accumulation of FA in SkM has been suggested to contribute to metabolic diseases such as obesity and type 2 diabetes mellitus. Consequently, there is significant interest in SkM FA metabolism and importantly, how FAs contribute to the metabolic function...